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Condition guide · /erectile-dysfunction/
Erectile dysfunction treatment online
Reviewed by Dr. Arjun Mehta, PharmD — Head Pharmacist. Updated May 2025.
1 in 3
Men over 40 affected
95%
Respond to PDE5 treatment
4
FDA-approved medicines
95%
Cheaper than brand
ED medicines in this guide
From $30
From $32
From $38
From $92
From $41
What is erectile dysfunction?
Erectile dysfunction (ED) is the inability to achieve or maintain an erection firm enough for sexual intercourse. It affects an estimated 30 million men in the United States and becomes more common with age, though it can occur at any age.
ED can have physical causes (cardiovascular disease, diabetes, low testosterone, obesity) or psychological causes (stress, anxiety, depression). In many men, it’s a combination of both. The good news: it’s one of the most treatable medical conditions, with oral medications (PDE5 inhibitors) effective in over 95% of cases.
ED treatment options
Sildenafil (generic Viagra)
Works in 30–60 min. Lasts 4–6 hours. Most prescribed. Available from $30.
Tadalafil (generic Cialis)
Works in 30 min. Lasts up to 36 hours. Daily dose option. From $38.
Avanafil (generic Stendra)
Fastest-acting. Works in as little as 15 min. Fewer side effects. From $92.
Vardenafil (generic Levitra)
Good for men with diabetes. Similar profile to sildenafil. From $45.
Dr. Arjun Mehta, PharmD · Head Pharmacist
/our-pharmacists/arjun-mehta/ — Reviewed May 2025
For most men with no cardiovascular contraindications, sildenafil 50mg is an excellent starting point. If you want spontaneity, tadalafil's 36-hour window is hard to beat. If speed matters, avanafil is the fastest-acting option we stock. Do not take any PDE5 inhibitor with nitrate medications — this combination can cause a dangerous drop in blood pressure.
