Reviewed by Dr. Arjun Mehta, PharmD — Head Pharmacist. Updated May 2025.
Have Alzheimer’s
Main drug classes
Alzheimer’s disease is the most common cause of dementia. Current medications do not cure it but can modestly slow cognitive decline and ease behavioural symptoms in some patients. Earlier diagnosis means earlier treatment and better planning.
Two main drug groups are used: cholinesterase inhibitors (donepezil, rivastigmine, galantamine) for mild-to-moderate disease, and memantine (an NMDA antagonist) for moderate-to-severe disease. They can be combined. Newer disease-modifying antibodies are emerging but availability and eligibility are limited.
Cholinesterase inhibitor. Once daily, usually at night. Most prescribed Alzheimer’s medicine globally.
NMDA antagonist for moderate-severe disease. Can be combined with a cholinesterase inhibitor.
No. They slow decline modestly and can improve symptoms for a period — typically 6–12 months — but disease progresses despite treatment.
Cholinesterase inhibitors cause nausea, diarrhoea and weight loss in some patients. Start low, increase slowly.
After a confirmed Alzheimer’s diagnosis by a specialist. Earlier mild cognitive impairment is not usually treated.

/our-pharmacists/arjun-mehta/ — Reviewed May 2025
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