ivermectin
What Are Ivermectin?ย
Ivermectin is a macrocyclic lactone antiparasitic agent on the WHO Model List of Essential Medicines, with a remarkable safety record and broad-spectrum activity against nematodes and ectoparasites. Originally discovered in the 1970s and awarded the Nobel Prize for Medicine in 2015, Ivermectin has transformed the treatment and control of Onchocerciasis (river blindness), Lymphatic filariasis, and Strongyloidiasis globally. AmozonPill stocks 26 generic Ivermectin products sourced from FDA-inspected, WHO-GMP manufacturers at up to 95% below brand-name prices.ย
Drug Classes Availableย
- Oral Ivermectin โ 3 mg, 6 mg, 12 mg Tablets:ย Standard formulation for systemic antiparasitic treatment. Dose is weight-based (200 mcg/kg). Available in 3 mg, 6 mg, and 12 mg tablets. Used for Strongyloidiasis, Onchocerciasis, Scabies, and Lymphatic filariasis.ย
- Topical Ivermectin:ย 1% cream โ FDA-approved for rosacea-associated papulopustular lesions. Also used off-label for head lice and demodicosis (Demodex mite infestation of eyelashes/face).ย
- Combination Products:ย Ivermectin + Albendazole โ used in mass drug administration (MDA) programmes for Lymphatic filariasis and soil-transmitted helminths. Provides dual-mechanism antiparasitic coverage.ย
Why Buy Generic?ย
- Generic Ivermectin 12 mg from $18 vs $80+ for Stromectol brandย
- WHO Essential Medicine โ same quality standard as originator productย
- FDA-inspected, WHO-GMP-certified manufacturersย
- Available in multiple strengths for weight-based dosingย
- Free shipping on orders over $199ย
How to Choose the Right Productย
For Strongyloidiasis: Ivermectin 200 mcg/kg as a single dose โ repeat after 2 weeks in hyperinfection syndrome. For Scabies: Ivermectin 200 mcg/kg single dose, repeated at day 14; for crusted/Norwegian scabies, multiple doses with topical Permethrin. For Onchocerciasis: Ivermectin 150 mcg/kg annually or semi-annually as part of elimination programmes. For head lice: topical 0.5% Ivermectin lotion applied once. Ivermectin should be taken on an empty stomach with water.ย
For Strongyloidiasis: Ivermectin 200 mcg/kg as a single dose โ repeat after 2 weeks in hyperinfection syndrome. For Scabies: Ivermectin 200 mcg/kg single dose, repeated at day 14; for crusted/Norwegian scabies, multiple doses with topical Permethrin. For Onchocerciasis: Ivermectin 150 mcg/kg annually or semi-annually as part of elimination programmes. For head lice: topical 0.5% Ivermectin lotion applied once. Ivermectin should be taken on an empty stomach with water.ย
Frequently Asked Questions
What is Ivermectin used for medically?ย
Ivermectin’s primary approved indications are Strongyloidiasis (intestinal threadworm), Onchocerciasis (river blindness), Lymphatic filariasis, Scabies, and head lice. It is a WHO Essential Medicine with over 4 billion doses administered globally since the 1980s.ย
How does Ivermectin kill parasites?ย
Ivermectin binds selectively to glutamate-gated chloride channels in invertebrate nerve and muscle cells, causing paralysis and death of the parasite. These channels do not exist in mammals, which explains its high safety margin in humans at therapeutic doses.ย
Is Ivermectin effective against COVID-19?ย
No. Multiple large, well-designed randomised controlled trials (including the WHO Solidarity Trial and the TOGETHER Trial) have found no clinically meaningful benefit of Ivermectin in COVID-19 treatment or prevention. Major health authorities (WHO, FDA, EMA) do not recommend Ivermectin for COVID-19.ย
What is the correct dose of Ivermectin for scabies?ย
The standard dose is 200 mcg/kg body weight as a single oral dose, repeated 14 days later. For a 70 kg adult this is approximately 14 mg (one 12 mg tablet + one 3 mg tablet). Treat all close household contacts simultaneously. Combine with topical Permethrin for crusted scabies.ย
Can Ivermectin be taken with food?ย
No โ Ivermectin oral tablets should be taken on an empty stomach (at least 2 hours before or after a meal) with a full glass of water. High-fat food significantly increases Ivermectin bioavailability, potentially increasing both efficacy and side effect risk.ย
Is long-term Ivermectin use safe?ย
At WHO-recommended doses for approved indications, Ivermectin has an excellent safety profile even with repeated use in mass administration programmes. The main side effects are mild and transient: dizziness, nausea, pruritus. The Mazzotti reaction (fever, rash, oedema) can occur in Onchocerciasis patients as dying microfilariae release antigens.ย
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